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Pramod Jog

Pramod Jog

Dr. D. Y. Patil Medical College, India

Title: Immunology as applied to vaccination

Biography

Biography: Pramod Jog

Abstract

The main aim of the immune system is to recognize self from foreign and to eliminate the harmful foreign substances from the body. This is done through recognition of antigens on the foreign substances or organisms. The response mounted by the body is called immune response and it consists of producing either proteins called antibodies as in humoral response or specific cells called cellular response. The antigen (Ag) is presented to the Antigen Presenting Cell (APC). The Ag-APC complex reaches the lymph node and stimulates either CD4 (helper) or CD8 (cytotoxic) T cell. The CD4 T cell produces either Th1 or Th2 cells. Th2 cells stimulate B cells to produce either plasma cells or memory cells. Plasma cells produce antibodies. The presentation will discuss the dynamics of antibody production; primary response, secondary response, immunological basis of conjugated vaccines etc.